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Reishi Mushrooms and Cancer: A Promising Area of Research

Reishi mushrooms, also known as Ganoderma lucidum, have been used for centuries in traditional medicine for their potential health benefits. These mushrooms are native to Asia and have been used to treat a variety of ailments, including respiratory conditions, liver disorders, and fatigue. Recently, there has been growing interest in the potential anticancer activity of these mushrooms.

Red Reishi mushroom

Reishi mushroom (Ganoderma lucidum) is a potent immune system regulator, promising anti-cancer agent, and stress reducer. This mushroom is frequently used in traditional Chinese medicine. There are currently over 24 clinical trials in the works to study reishi, making it one of the most prominent and well-studied medicinal mushrooms over the coming years. These studies encompass a variety of research including possible treatments for cancer, colitis, Parkinson’s and overall immune function .


Here is a brief overview of some of the research on reishi mushroom from the past few years:

  • In patients with coronary heart disease and hyperlipidemia, reishi has been studied for its ability to alleviate symptoms such as palpitations, dyspnea (sudden difficulty in breathing), precordial pain, and edema, and it seems to lower blood cholesterol and blood pressure. G. lucidum has also been used to treat heart arrhythmias.

  • Reishi mushroom contains complex sugars known as beta-glucans. Lab studies suggest that these compounds may help stop the growth and spread of cancer cells. When animals were fed beta-glucans, some cells of their immune system became more active. Limited data from clinical studies suggest reishi can strengthen immune response in humans.

  • In vitro studies suggest that triterpenes and polysaccharides of the Reishi mushroom affect cell signaling in cancer cells. Several studies demonstrate that extracts of Reishi mushrooms downregulate VEGF 1,2 and MAPK signaling, 3,4 as well as induce cell cycle arrest, apoptosis, and/or autophagy

  • Reishi mushroom has shown anticancer activity in vitro studies, studies done in animal models, and human studies. The Reishi mushroom fights cancerous cells in the lung, white blood cells, liver, breast, prostate, uterus, cervix, ovaries, colon, and bladder.

While more research is needed to fully understand the potential anticancer activity of Reishi mushrooms, these early findings are promising. It is thought that the complex sugars known as beta-glucans Polysaccharides found in Reishi mushrooms may help stop the growth and spread of cancer cells by enhancing the immune response.


As with any supplement or treatment, it is important to consult with a healthcare professional before

incorporating Reishi mushrooms into your healthcare regimen. While these mushrooms are generally considered safe for consumption, they may interact with certain medications or have side effects in some individuals.


Most importantly, the quality of the reishi is crucial to rip any benefits out of it. If you choose to consume reishi mushroom, ensure that it is of high quality and potency with the largest percentage of beta-glucans polysaccharides such as Reishi Essence ProFormula or GanoPrime.


In conclusion, Reishi mushrooms are a promising area of research in the fight against cancer. While more studies are needed to fully understand their potential anticancer activity, early findings suggest that these mushrooms may have a role to play in enhancing the immune response and stopping the growth and spread of cancer cells.

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